Mikala Egeblad
Associate Professor

Mikala obtained degrees in Medicine (B.S., 1993). Human Biology (M.Sc., 1996), and in Cancer Biology (Ph.D., 2000) from the University of Copenhagen, Denmark. She did her dissertation research under the mentorship of Dr. Marja Jäättelä at The Danish Cancer Society. Her postdoctoral training was performed in the laboratory of Dr. Zena Werb at University of California, San Francisco. There, she began developing intravital spinning disk confocal microscopy to understand how the microenvironment influences tumor progression, focusing on innate immune cell responses and protease-mediated extracellular matrix remodeling. She came to Cold Spring Harbor Laboratory in 2009 and established a research group that studies how the tumor microenvironment contributes to therapy resistance and metastasis, primarily focusing on the role of inflammatory cells. In 2014, she was promoted to Associated Professor. She received the Department of Defense Breast Cancer Research Program Era of Hope Scholar Award in 2014 and the Pershing Square Sohn Prize for Young Investigators in Cancer Research in 2017.

Jean Albrengues
Postdoctoral Fellow

Jean received his Ph.D. from the University of Nice-Sophia Antipolis, France. There, he focused on the role of the cytokine LIF during the activation and the epigenetic maintenance of pro-invasive fibroblasts, under the direction of Dr. Cedric Gaggioli. He joined the Egeblad lab in May 2015, and is working on determining how communications between tumor cells and neutrophils contribute to breast cancer cell dormancy and recurrence.

Xuyan He
Postdoctoral Fellow

Xueyan received her Ph.D. from Model Animal Research Center of Nanjing University, China. There, she examined the role of p53 in tumor microenvironment using genetically engineered mouse models, under the direction of Professor Geng Liu. She joined the Egeblad lab in September 2016 and is currently investigating the interactions and signaling pathways between cancer cells and tumor stroma cells, (especially T cells and dendritic cells). She is interested in mechanisms of immune suppression and cancer immunotherapy.

Lijuan Sun
Postdoctoral Fellow

Lijuan received her Ph.D. from Sun Yat-sen University, China, where she studied the roles of long noncoding RNAs and microRNAs in the biology of breast cancer and oral cancer. Lijuan joined the Egeblad lab in June 2017. She is interested in the molecular mechanisms of tumor-stromal interactions in breast cancer.

Juliane Daßler-Plenker
Postdoctoral Fellow

Juliane received her Ph.D. from the University of Bonn, Germany, where she examined the role of RIG-I in anti-tumor immunity mediated by extracellular vesicles and natural killer cell activation under the direction of Prof. Gunther Hartmann. She joined the Egeblad lab in October 2017 and is currently investigating how neutrophil extracellular traps impact the immune system to promote awakening of dormant cancer cells.

Harrison Seidner
Postdoctoral Fellow

Harrison received his Ph.D. in Biomedical Engineering from Stony Brook University, NY. There he developed a custom microscope and a microfluidic apparatus to study the contribution of surface nanobubbles to cell-cell interactions under the direction of Dr. Mary Frame. He joined the Egeblad Lab in May 2018, and is engineering systems for intravital multi-photon microscopy to study cancer cells in their natural environment.

Laura Maiorino
Graduate Student, Watson School of Biological Sciences

Laura received her M.S in Medical, Molecular and Cellular Biotechnology from the San Raffaele University in Milan, Italy. Since 2013 she is a graduate student in the Watson School of Biological Sciences at Cold Spring Harbor Laboratory. She joined the Egeblad Lab in 2014 to study the molecular pathways underlying organ specificity and dormancy of liver metastasis.

Emilis Bruzas
Graduate Student, Watson School of Biological Sciences

Emilis obtained his BA in Natural Sciences with a concentration in Biochemistry from the University of Cambridge in 2014. He joined the Watson School of Biological Sciences the same year and has been a member of the Egeblad lab since 2015. Emilis studies the interplay between the immune system and stem cell behavior in a model of breast cancer dormancy.

Margaret Shevik
Graduate Student, MD/PhD, Stony Brook University

Margaret joined the Egeblad lab in 2018 and is studying the effects of neutrophil extracellular traps in integrin signaling and metastasis.
 

Jenesis Curtis
Laboratory Technician

Jenesis received her B.A in Biology from Hofstra University in 2016 with a focus in pre-veterinary science. She joined the Egeblad Lab in 2017 and manages the lab, the experimental mouse colonies, as well as assists in animal experiments lead by research lab members.

David Ng
Laboratory Technician

David received his B.S. in Biochemistry from Stony Brook University. He joined the Egeblad Lab in August of 2017. He is working on the influences of the microenvironment in disease progression, with Jean as his mentor. David also participates in managing the lab’s mouse colony.

Catherine Scalise
Administrative Assistant 

Cathy is the Egeblad lab’s administrative assistant.