Recent publications

Park, J., Wysocki, R.W., Amoozgar, Z., Maiorino, L., Fein, M.R., Jorns, J., , Schott, A.F., Kinugasa-Katayama, Y., Lee, Y., Won, N.H., Nakasone, E.S., Hearn, S.A., Küttner,V., Qiu, J., Almeida, A.S., Perurena, N., Kessenbrock, K., Goldberg M.S., and Egeblad. M. (2016) Cancer cells trigger neutrophils to induce metastasis-supporting extracellular DNA traps. Sci. Transl. Med. 8, 361ra138 Abstract Full text PDF reprint

Arun, G., Diermeier, S., Akerman, M., Chang, K.-C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A.R., Krainer, A., Norton, L., Brogi, E., Egeblad, M. and Spector, D. L. Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss. Genes Dev, 30, 34-51.

Park, J.-H., Rasch, M.R., Qiu J., Lund I.K., Egeblad, M. (2015) Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer. Neoplasia, 17, 421-33.

Ewald, A.J. and Egeblad M. (2014) Cancer: Sugar-coating cell signalling. Nature, 51:298-9.

Fein, M. R., and Egeblad, M. (2013) Caught in the Act: Revealing the Metastatic Process by Live Imaging. Dis. Model Mech., 6(3):580-93. doi: 10.1242/dmm.009282.

Rajaram M., Li J., Egeblad M., Powers R.S. (2013) System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenecity. PLoS Genet, 9(9):e1003789.

Nakasone, E. S, Askautrud, H. A., and Egeblad, M. (2013) Live imaging of drug responses in the tumor microenvironment in mouse models of breast cancer. J Vis Exp, 73, doi: 10.3791/50088.

Nakasone, E.S., Askautrud, H.A., Kees , T., Parks, J.-H., Plaks, V., Ewald, A.J., Fein, M., Rasch, M.G., Tan, Y.X., Qiu, J., Park, J., Sinha, P., Bissell, M., Frengen, E., Werb, Z., and Egeblad, M. (2012) Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell, 21, 488-503. Selected for the cover. See also Research Highlights, Nature 2012, 485, 282.

Engelhardt, J.J., Boldajipour, B., Beemiller, P., Pandurangi, P., Sorenson, C., Werb, Z., Egeblad, M., and Krummel, M.F. (2012). Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer Cell, 21, 402-417.

Kees, T. and Egeblad, M. (2011). Innate immune cells in breast cancer – from villains to heroes? J Mammary Gland Biol Neoplasia, 16, 189-203.

Sounni, N.E., Dehne, K., van Kempen, L.C.L., Egeblad, M., Affara, N.I., Cuevas, I., Wisen J., Junankar, S., Korets, L., Lee, J., Shen, J., Morrison, C.J., Overall, C. M., Krane, S.M., Werb, Z., Boudreau, N., and Coussens, L.M. (2010). Stromal Regulation of Vessel Stability by MMP14 and TGFβ. Dis. Model. Mech., 3, 317-32.

Egeblad M., Rasch, M.G., and Weaver V.M. (2010). Dynamic interplay between the collagen scaffold and tumor evolution. Curr. Opin. Cell Biol., 22, 697-706.

Egeblad, M., Nakasone, E.S., and Werb, Z. (2010). The tumor as an organ: complex tissues that interface with the entire organism. Dev. Cell, 18, 884-901.

Levental, K.R., Yu, H., Kass, L., Lakins, J.N., Egeblad, M., Erler J.T., Fong, S.F., Csiszar, K.L., Giaccia, A., Weninger, W., Yamauchi, M., Gasser, D.L., and Weaver, V.M. (2009). Matrix cross-linking forces tumor progression by enhancing integrin signaling. Cell, 139, 891-906.